研究队伍
![](http://former.rcees.ac.cn/uploadfile/2016/0311/20160311050519571.jpg)
简历:
2005.9 - 2009.7 吉林大学 化学学院 化学专业 大学本科
2009.9 – 2014.6 吉林大学 理论化学研究所 物理化学专业 博士研究生-
2014.7- 至今 中国科学院生态环境研究中心 环境化学与生态毒理学国家重点实验室 助理研究员
社会任职:
承担科研项目:
国家自然科学青年基金项目(主持):典型污染物通过配体结合域表面位点作用影响核受体介导效应的理论研究,年限:2016.1-2018.12
获奖及荣誉:
代表论著:
- Qiao Xue, Ji-Long Zhang, Qing-Chuan Zheng, Ying-Lu Cui, Lin Chen, Wen-Ting Chu, and Hong-Xing Zhang, "Exploring the Molecular Basis of dsRNA Recognition by Mss116p Using Molecular Dynamics Simulations and Free-Energy Calculations" Langmuir, 2013, 29(35): 11135-11144.
- Qiao Xue, Qing-Chuan Zheng, Ji-Long Zhang, Ying-Lu Cui, and Hong-Xing Zhang, "Exploring the mechanism how Marburg virus VP35 recognizes and binds dsRNA by molecular dynamics simulations and free energy calculations." Biopolymers, 2014, 101(8): 849-860.
- Qiao Xue, Qing-Chuan Zheng, Ji-Long Zhang, Ying-Lu Cui, Wen-Ting Chu, and Hong-Xing Zhang, "Mutation and low pH effect on the stability as well as unfolding kinetics of transthyretin dimer", Biophysical chemistry, 2014, 189: 8-15.
- Lin Chen, Ji-Long Zhang, Li-Ying Yu, Qing-Chuan Zheng, Wen-Ting Chu, Qiao Xue, Hong-Xing Zhang, and Chia-Chung Sun, "Influence of hyperthermophilic protein Cren7 on the stability and conformation of DNA: insights from molecular dynamics simulation and free energy analysis", The Journal of Physical Chemistry B, 2012, 116(41): 12415-12425.
- Wen-Ting Chu, Yun-Jian Wu, Ji-Long Zhang, Qing-Chuan Zheng, Lin Chen, Qiao Xue, and Hong-Xing Zhang, "Constant pH Molecular Dynamics (CpHMD) and mutation studies: insights into AaegOBP1 pH-induced ligand releasing mechanism", Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics, 2012, 1824(7): 913-918.
- Lin Chen, Qing-Chuan Zheng, Li-Ying Yu, Wen-Ting Chu, Ji-Long Zhang, Qiao Xue, Hong-Xing Zhang, and Chia-Chung Sun, "Insights into the thermal stabilization and conformational transitions of DNA by hyperthermophile protein Sso7d: molecular dynamics simulations and MM-PBSA analysis", Journal of Biomolecular Structure and Dynamics, 2012, 30(6): 716-727.
- Ying-Lu Cui, Qing-Chuan Zheng, Ji-Long Zhang, Qiao Xue, Yan Wang, and Hong-Xing Zhang, "Molecular Dynamic Investigations of the Mutational Effects on Structural Characteristics and Tunnel Geometry in CYP17A1", Journal of Chemical Information and Modeling, 2013, 53(12): 3308-3317.
- Wen-Ting Chu, Ji-Long Zhang, Qing-Chuan Zheng, Lin Chen, Yun-Jian Wu, Qiao Xue, and Hong-Xing Zhang, "Constant pH molecular dynamics (CpHMD) and molecular docking studies of CquiOBP1 pH-induced ligand releasing mechanism", Journal of Molecular Modeling, 2013, 19(3): 1301-1309.
- Lin Chen, Ji-Long Zhang, Qing-Chuan Zheng, Wen-Ting Chu, Qiao Xue, Hong-Xing Zhang, and Chia-Chung Sun, "Influence of C-terminal tail deletion on structure and stability of hyperthermophile Sulfolobus tokodaii RNase HI", Journal of Molecular Modeling, 2013, 19(6): 2647-2656.
- Wen-Ting Chu, Ji-Long Zhang, Qing-Chuan Zheng, Lin Chen, Qiao Xue, and Hong-Xing Zhang, "Insights into the drug resistance induced by the BaDHPS mutations: molecular dynamic simulations and MM/GBSA studies", Journal of Biomolecular Structure and Dynamics, 2013, 31(10): 1127-1136.
- 12. Wen-Ting Chu, Qing-Chuan Zheng, Yun-Jian Wu, Ji-Long Zhang, Chong-Yang Liang, Lin Chen, Qiao Xue, and Hong-Xing Zhang, "Molecular dynamics (MD) simulations and binding free energy calculation studies between inhibitors and type II dehydroquinase (DHQ2)", Molecular Simulation, 2013, 39(2): 137-144.
- 13. 吕冰聪, 董森, 薛峤, 宗慧, 吕绍武, &罗贵民, “具有谷胱甘肽过氧化物酶活力的含碲环糊精衍生物”, 高等学校化学学报, 2013, 34(9): 2146-2151.