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姓名:尹俊发 [硕士生导师] 性别:男职称: 副研究员 电话:010-62849611E-mail:jfyin@rcees.ac.cn组别:DNA修饰与分子毒理研究组 研究方向:DNA损伤检测;整体型色谱分离介质及分子印迹材料开发招生专业:环境科学,分析化学

简历:

         尹俊发,理学博士,硕士生导师。2000年、2004年于河北大学化学与环境科学学院获学士、硕士学位;2007年于中国科学院化学研究所获理学博士学位;2007年至今,中国科学院生态环境研究中心环境化学与生态毒理学国家重点实验室副研究员。主要从事分析化学和环境化学领域的研究,包括:DNA损伤的高选择性和高灵敏度检测;整体型色谱分离介质及分子印迹材料用于环境污染物检测;纳米识别材料的开发及在环境污染物检测中的应用等。主持国家自然科学基金2项,参与在研或完成国家研发计划、973863项目的任务(子课题)8项;中科院战略先导专项B子课题1项。在Anal. Chem., Chem. Commun., J. Chromatogr. A等学术期刊发表论文52篇,SCI 收录44篇,他引800余次。

社会任职:

中国化学会会员
中国毒理学会会员

承担科研项目:

1. 国家重点研发专项,2016YFA0203102,纳米材料治理水体复合污染物的应用基础研究及工程示范,2017.01-2021.1280万元,在研,参加

2. 中国科学院战略先导科技专项B之课题,XDB14030302,污染物诱发核酸损伤类型的鉴定,2014.07-2019.06143万元,在研,主持

3. 国家自然科学基金面上项目,21375142,特异性识别DNA损伤的新型分子印迹纳米材料的设计、合成及应用,2014.01-2017.1280万元,已结题,主持

4. 国家自然科学基金青年项目,20805057,原子转移自由基聚合法制备新型分子印迹纳米膜包覆型毛细管整体柱,2009.01-2011.1218万元,已结题,主持

获奖及荣誉:

中国分析测试协会科学技术奖(CAIA奖)一等奖,高灵敏DNA修饰分析新方法,2013年(排名第八)

中国分析测试协会科学技术奖(CAIA奖)特等奖,高灵敏DNA甲基化与去甲基化修饰分析新方法,2015年(排名第七)

代表论著:

1.    Junfa Yin, Shaokun Chen,Ning Zhang, Hailin Wang*. Multienzyme Cascade Bioreactor for a 10 min Digestion of Genomic DNA into Single Nucleosides and Quantitative Detection of Structural DNA Modifications in Cellular Genomic DNA. ACS Applied Materials & Interfaces, 2018, 10, 21883−21890.

2. Junfa Yin, Tian Xu, Ning Zhang, Hailin Wang, Three-Enzyme Cascade Bioreactor for Rapid Digestion of Genomic DNA into Single Nucleosides, Analytical Chemistry, 2016, 88, 7730-7737.

3. Junfa Yin, Yuanyuan Song, Ning Zhang, Tian Xu, Hailin Wang, A fluorophore-conjugated ascorbic acid functions for the visualization of sodium vitamin C transporters in living cells, Analytical Methods, 2015, 7, 9663-9672.

4. Junfa Yin, Zhixin Wang, Maoyong Song, Chao Zhao, Hailin Wang, Plastic antibody for DNA damage: fluorescent imaging of BPDE-dG adducts in genomic DNA, Analyst, 2013, 138, 4958-4966.

5. Junfa Yin, Zihui Meng, Yishan Zhu, Maoyong Song, Hailin Wang, Dummy molecularly imprinted polymer for selective screening of trace bisphenols in river water. Analytical Methods, 2011, 3, 173–180.

6. Junfa Yin, Yue Cui, Gengliang Yang, Hailin Wang, Molecularly imprinted nanotubes for enantio-selective drug delivery and controlled release. Chemical Communications, 2010, 46, 7688–7690.Cover story

7. Junfa Yin, Zihui Meng, Mingjun Du, Cong Liu, Maoyong Song, Hailin Wang, Pseudo-template molecularly imprinted polymer for selective screening of trace β-lactam antibiotics in river and tap water. Journal of Chromatography A, 2010, 1217, 5420–5426.

8. Junfa Yin, Yuling Song, Zhixin Wang, Hailin Wang, Fabrication and fluorescence imaging of human low-density lipoprotein coatings for highly efficient capillary electrophoresis separation of basic proteins. Electrophoresis, 2009, 30, 1362–1371.

9. Junfa Yin, Lijuan Wang, Xiaoyi Wei, Gengliang Yang, Hailin Wang, p-tert-Butylcalix[8]arene-bonded silica monoliths for liquid chromatography. Journal of Chromatography A, 2008, 1188, 199-207.

10. Junfa Yin, Gengliang Yang, Hailin Wang, Yi Chen, Macroporous polymer monoliths fabricated by using a metal-organic coordination gel template. Chemical Communications, 2007, 44, 4614–4616.

11. Junfa Yin, Gengliang Yang, Yi Chen, Rapid and efficient chiral separation of nateglinide and its L-enantiomer on monolithic molecularly imprinted polymers. Journal of Chromatography A, 2005, 1090, 68-75.