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姓名:高明性别:男职称: 助理研究员 电话:62849050E-mail:minggao@rcees.ac.cn组别:环境污染与健康效应研究组 研究方向:环境毒理学,基因表达和调控

简历:

2011/09- 2014/07,天津大学,制药工程,博士

2007/09- 2010/07,中国人民解放军军事医学科学院,免疫学,硕士

2003/09- 2007/07,吉林大学,制药工程,学士

2014/7-至今,中国科学院生态环境研究中心,环境化学与生态毒理学国家重点实验室,环境污染与健康效应研究组,助理研究员。

承担科研项目:

1. 国家自然科学基金青年科学基金项目,21507154,低剂量纳米银的红系发育毒性及分子机制研究,2016/01-2018/1225.9万元,在研,主持

2. 中国科学院战略性先导科技专项(B)XDB14000000、典型污染物的环境暴露与健康危害机制、2014/07-2019/733.4万元,在研、参与

代表论著:

1Ming Gao, Yun Liu, Yue Chen, ChunyangYin, Jane-JaneChen, SijinLiu, miR-214 protects erythroid cells against oxidative stress by targeting ATF4 and EZH2. FREE RADICAL BIO MED.2016, 92:39-49.

2Ming Gao, Yi-Qun Zhan, Miao Yu, Chang-Hui Ge, Chang-Yan Li, Jian-Hong Zhang, Xiao-Hui Wang, Zhi-Qiang Ge and Xiao-Ming Yang, Hepassocin Activates the EGFR/ERK Cascade and Induces Proliferation of L02 Cells through the Src kinase-Dependent Pathway. Cell Signal. 2014, 26:2161–2166

3. Ming Gao, Xiaoguang Li, Wen Dong, Rui Jin, Hanghang Ma, Pingxun Yang, Meiru Hu, Yi Li, Yi Hao, Shengtao Yuan, Junjian Huang and Lun Song. Ribosomal  protein S7 regulates arsenite-induced GADD45α expression by attenuating MDM2-mediated GADD45α ubiquitination and degradation. Nucleic Acids Res. 2013, May 1;41(10):5210-22

4. Li Y#, Hao Y#, Gao M#, Dong W, Hu M, Yuan S, Song L. IKKβ downregulation is critical for triggering JNKs-dependent cell apoptotic response in the human hepatoma cells under arsenite exposure. Mol Cell Biochem. 2011 Dec;358(1-2):61-6.

5. Gao M, Dong W, Hu M, Yu M, Guo L, Qain L, Guo N, Song L. GADD45a mediates arsenite-induced cell apoptotic effect in human hepatoma cells via JNKs/AP-1-dependent pathway. J Cell Biochem 2010, 109: 1264-1273

6. Gao M, Guo N, Huang C, Song L. Diverse roles of GADD45a in stress signaling. Curr Protein Pept Sci, 2009, 10: 388-394