研究队伍
姓名：徐明 [硕士生导师] 性别：男职称： 副研究员 电话：E-mail：mingxu@rcees.ac.cn组别：环境污染与健康效应研究组
简历：
2002-2006，厦门大学，化学系，学士
2006-2011，厦门大学，化学系，博士
2011-2013，法国国家科学研究中心（CNRS），博士后
2014-2015，中国科学院生态环境研究中心，助理研究员
2016-至今，中国科学院生态环境研究中心，副研究员
目前主要研究方向（1）基于组学（蛋白组学、金属组学等）的毒理学研究；（2）微纳颗粒物的生物学机制研究。已在ACS Nano，Chemistry-A European Journal，Analytical Chemistry等国际知名期刊上发表SCI论文18篇，累计被引用超过270余次。
承担科研项目：
国家自然科学基金青年基金项目：基于金属组学揭示纳米银肝细胞毒性的分子机制
国家重点基础研究发展计划（973计划）项目子课题：典型人工纳米材料的水环境过程、生物效应及其调控研究
国家重点基础研究发展计划（973计划）项目子课题：耐极端条件的有机含氟纳米材料的研究
代表论著：
1. Zhu, J.; Xu, M.;* Gao, M.; Zhang, Z.; Xu, Y.; Xia T.; Liu, S.* Graphene Oxide Induced Perturbation to Plasma Membrane and Cytoskeletal Meshwork Sensitize Cancer Cells to Chemotherapeutic Agents. ACS Nano 2017, 11, 2637-2651.
2. Xu, M.;# Zhu, J.;# Wang, F.; Xiong, Y.; Wu, Y.; Wang, Q.; Weng, J.;* Zhang, Z.;* Chen, W.; Liu, S.* Improved In Vitro and In Vivo Biocompatibility of Graphene Oxide through Surface Modification: Poly(Acrylic Acid)-Functionalization is Superior to PEGylation. ACS Nano 2016, 10, 3267-3281.
3. Guo, W.;# Zhang, J.;# Li, W.; Xu, M.;* Liu, S.* Disruption of iron homeostasis and resultant health effects upon exposure to various environmental pollutants: A critical review. Journal of Environmental Sciences, 2015, 34, 155-164.
4. Xu, M.; Yang, L. M.; Wang, Q. Q.* Se-Hg Dual-element Labeling Strategy for Selectively Recognizing Selenoprotein and Selenopeptide. Chinese Journal of Analytical Chemistry, 2015, 43, 1265-1271. (cover paper)
5. Xu, M.; Frelon, S.; Simon, O.; Lobinski, R.; Mounicou, S.* Development of a non-denaturing 2D gel electrophoresis protocol for screening in vivo uranium-protein targets in Procambarus clarkii with laser ablation ICP MS followed by protein identification by HPLC–Orbitrap MS. Talanta, 2014, 128, 187-195.
6. Xu, M.; Bijoux H.; Gonzalez P.; Mounicou, S.* Investigating the response of cuproproteins from oysters (Crassostrea gigas) after waterborne copper exposure by metallomic and proteomic. Metallomics, 2014, 6, 338-346.
7. Xu, M.; Frelon, S.; Simon, O.; Lobinski, R.; Mounicou, S.* Non-denaturating isoelectric focusing gel electrophoresis for uranium–protein complexes quantitative analysis with LA-ICP MS. Analytical and Bioanalytical Chemistry, 2014, 406, 1063-1072.
8. Xu, M.; Yang, L. M.; Wang, Q. Q.* Chemical interactions of mercury species and some transition and noble metals towards metallothionein (Zn7MT-2) evaluated using SEC/ICP-MS, RP-HPLC/ESI-MS and MALDI-TOF-MS. Metallomics, 2013, 5, 855-860.
9. Xu, M.; Yang, L. M.; Wang, Q. Q.* A way to probe the microenvironment of free sulfhydryls in intact proteins with a series of monofunctional organic mercurials. Chemistry - A European Journal, 2012, 18, 13989-13993.
10. Xu, M., Deng, G. F., Liu, S. S., Chen, S., Cui, D., Yang, L. M., Wang, Q. Q.* Free cadmium ions released from CdTe-based nanoparticles and their cytotoxicity on Phaeodactylum tricornutum. Metallomics, 2010, 2, 469-473.
11. Xu, M., Yan, X. W., Xie, Q. Q., Yang, L. M., Wang, Q. Q.* Dynamic labeling strategy with 204Hg-isotopic methylmercurithiosalicylate for absolute peptide and protein quantification. Analytical Chemistry, 2010, 82, 1616-1620.
12. Xu, M., Yang, L. M., Wang, Q. Q.* Quantification of selenium-tagged proteins in human plasma using species-unspecific isotope dilution ICP-DRC-qMS coupled on-line with anion exchange chromatography. Journal of Analytical Atomic Spectrometry, 2008, 23, 1545-1549.