CHINESE
04-21-2019

Crew

Name Ming Xu Gender male
Phone 8610-62849050 Email 8610-62849050
Group name Environmental Pollution and Health Impact
Reserch
interest
To explore the biological and toxicological mechanisms of (1) micro/nanoparticles and (2) heavy metals and evaluate their environmental and health risks.

Education and Appointments

2002-2006, B.S., Chemistry Department, Xiamen University, China

2006-2011 Ph.D., Chemistry Department, Xiamen University, China

2011-2013, Postdoctoral Fellow, Centre national de la recherche scientifique (CNRS), France

2014-2015, Assistant professor, Research Center for Eco-Environmental Sciences (RCEES), Chinese Academy of Sciences

2016-Present, Associate professor, Research Center for Eco-Environmental Sciences (RCEES), Chinese Academy of Sciences

Selected Publications

1.     Xu, M.;# Zhu, J.;# Wang, F.; Xiong, Y.; Wu, Y.; Wang, Q.; Weng, J.;* Zhang, Z.;* Chen, W.; Liu, S.* Improved In Vitro and In Vivo Biocompatibility of Graphene Oxide through Surface Modification: Poly(Acrylic Acid)-Functionalization is Superior to PEGylation. ACS Nano 2016, 10, 3267-3281.

2.    Guo, W.;# Zhang, J.;# Li, W.; Xu, M.;* Liu, S.* Disruption of iron homeostasis and resultant health effects upon exposure to various environmental pollutants: A critical review. Journal of Environmental Sciences, 2015, 34, 155-164.

3.   Xu, M.; Yang, L. M.; Wang, Q. Q.* Se-Hg Dual-element Labeling Strategy for Selectively Recognizing Selenoprotein and Selenopeptide. Chinese Journal of Analytical Chemistry, 2015, 43, 1265-1271. (cover paper)

4.     Xu, M.; Frelon, S.; Simon, O.; Lobinski, R.; Mounicou, S.* Development of a non-denaturing 2D gel electrophoresis protocol for screening in vivo uranium-protein targets in Procambarus clarkii with laser ablation ICP MS followed by protein identification by HPLC–Orbitrap MS. Talanta, 2014, 128, 187-195.

5.    Xu, M.; Bijoux H.; Gonzalez P.; Mounicou, S.* Investigating the response of cuproproteins from oysters (Crassostrea gigas) after waterborne copper exposure by metallomic and proteomic. Metallomics, 2014, 6, 338-346.

6.     Xu, M.; Frelon, S.; Simon, O.; Lobinski, R.; Mounicou, S.* Non-denaturating isoelectric focusing gel electrophoresis for uranium–protein complexes quantitative analysis with LA-ICP MS. Analytical and Bioanalytical Chemistry, 2014, 406, 1063-1072.

7.   Xu, M.; Yang, L. M.; Wang, Q. Q.* Chemical interactions of mercury species and some transition and noble metals towards metallothionein (Zn7MT-2) evaluated using SEC/ICP-MS, RP-HPLC/ESI-MS and MALDI-TOF-MS. Metallomics, 2013, 5, 855-860.

8.    Xu, M.; Yang, L. M.; Wang, Q. Q.* A way to probe the microenvironment of free sulfhydryls in intact proteins with a series of monofunctional organic mercurials. Chemistry - A European Journal, 2012, 18, 13989-13993.

9.    Xu, M., Deng, G. F., Liu, S. S., Chen, S., Cui, D., Yang, L. M., Wang, Q. Q.* Free cadmium ions released from CdTe-based nanoparticles and their cytotoxicity on Phaeodactylum tricornutum. Metallomics, 2010, 2, 469-473.

10.  Xu, M., Yan, X. W., Xie, Q. Q., Yang, L. M., Wang, Q. Q.* Dynamic labeling strategy with 204Hg-isotopic methylmercurithiosalicylate for absolute peptide and protein quantification. Analytical Chemistry, 2010, 82, 1616-1620.

11.  Xu, M., Yang, L. M., Wang, Q. Q.* Quantification of selenium-tagged proteins in human plasma using species-unspecific isotope dilution ICP-DRC-qMS coupled on-line with anion exchange chromatography. Journal of Analytical Atomic Spectrometry, 2008, 23 (11), 1545-1549,.

Supported Projects

1.    Strategic Priority Research Program of the Chinese Academy of Sciences: Environmental exposure and health hazard mechanism of typical pollutants, 2014-2018. Type B.

2.    National “973” program: Study of environmental processes in water, consequential biological effects and correlative physicochemical regulations of the representative engineered nanomaterials, 2014-2018.

3.    National “973” program: Studies on organic fluorine-containing nanomaterials tolerant of extreme conditions, 2015-2019.

4.    Natural Science Foundation for the Youth (NSFY): Investigating the molecular mechanisms involved in the hepatic toxicity of Ag NPs based on the metallomic strategy, 2015-2017.